Which epilepsy drugs are safest in pregnancy?

A review of the risks of major congenital malformations and of adverse neurodevelopmental outcomes for antiepileptic drugs by the Commission on Human Medicines has confirmed that lamotrigine (Lamictal) and levetiracetam (Keppra) are the safer of the medicines reviewed during pregnancy.

Which seizure medication has the lowest risk of birth defects?

American Epilepsy Foundation President Daniel Lowenstein, MD, tells WebMD the good news from the Pennell study is the very low rate of problems seen with the newer seizure medication Lamictal.

Can you take epilepsy medication while pregnant?

Fact: You can. In fact, neurologists usually recommend continuing epilepsy medications throughout pregnancy. However, it comes down to the type of medication. You may need to adjust your dosage or switch to a new drug, but you probably won’t need to stop medication altogether.

Is levetiracetam safe in pregnancy?

Levetiracetam (LEV) is one such AED which is supposed to be effective in controlling seizures during pregnancy and relatively free of teratogenic side effects.

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Is vimpat safe during pregnancy?

Lacosamide is listed in Pregnancy Category C. This means that caution is advised, but the benefits of the medicine may outweigh the potential risks.

Is Tegretol safe in pregnancy?

Abstract. in English, French

Answer: Similar to valproic acid, carbamazepine increases the risk of neural tube defects; however, it does not increase the risk of other malformations. Carbamazepine is also not associated with an increased risk of developmental delay.

Which antiepileptic drugs cause fetal abnormalities?

Other anti-seizure medications can cause a characteristic pattern of mental and physical birth defects similar to those seen in infants exposed to phenytoin during pregnancy. Such drugs include valproate, carbamazepine, primidone, and phenobarbital.

How do you manage epilepsy during pregnancy?

In order to prevent convulsions during labour, proper seizure control should be achieved during the third trimester. Benzodiazepines or phenytoin are found to be effective for seizure cessation during labour and delivery. Phytomenadione should be administered immediately after birth to the newborn.

Can pregnancy cause non epileptic seizures?

Patients with psychogenic seizures onset after pregnancy. Two patients developed psychogenic seizures after learn- ing they were pregnant. Psychogenic seizure symptoms began shortly after pregnancy was confirmed, at 10 and 14 weeks of pregnancy respectively.

Is lamotrigine safe in pregnancy?

Pregnancy registries have consistently demonstrated lamotrigine to be among the safest medications for a developing fetus, both in terms of fetal malformations and postpartum cognitive development.

Is Keppra and Lamictal safe during pregnancy?

Recent studies carried out by the Commission on Human Medicines (CHM), looking at the risks associated with commonly prescribed AEDs shows that lamotrigine (Lamictal) and levetiracetam (Keppra) are safer to use during pregnancy than other AEDs, having low rates of physical birth abnormalities, in line with the …

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Is zonisamide safe during pregnancy?

Zonisamide may harm an unborn baby.

Use effective birth control to prevent pregnancy, and tell your doctor if you become pregnant.

What category is Keppra in pregnancy?

US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

What drug is comparable to Vimpat?


  • Vimpat (lacosamide) Prescription only. …
  • 7 alternatives.
  • Tegretol (carbamazepine) Prescription only. …
  • Dilantin (phenytoin) Prescription only. …
  • Lamictal (lamotrigine) Prescription only. …
  • Trileptal (oxcarbazepine) Prescription only. …
  • Zonegran (zonisamide) Prescription only. …
  • Banzel (rufinamide) Prescription only.

What is Levetiracetam used for?

Levetiracetam is a medicine used to treat epilepsy. Levetiracetam is available on prescription. It comes as tablets, a liquid and granules.

What pregnancy category is Abilify?

Safety of Psychiatric Medications During Pregnancy and Lactation

Drug FDA pregnancy category*
Aripiprazole (Abilify) C
Chlorpromazine (Thorazine)‡ C
Clozapine (Clozaril) B